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Balance is key: Deep lung microbial dynamics and host-microbe interactions.
Lower respiratory tract harbour characteristic microbial communities. We explored the deep lung microbiota dynamics of the transplanted lung over time. Our study shows that a predominant "balanced" microbiota resembling that of a healthy lung is key for clinical stability and immune homeostasis.
Bacterial promoters - a new direction
Bacterial promoters have always been considered to be directional, only recruiting RNAP in one orientation. In our paper, we show that promoters are frequently able to recruit polymerase in both orientations, resulting in divergent transcription. We call these bidirectional promoters.
Adaptating a cyanobacterium to extremely high light intensities
Using adaptive evolution for making photosynthetic microbes tolerant to stressful conditions might be a shortcut for identifying protein mutations suitable to enhance the yield of crop plants.
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Behind the paper
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Balance is key: Deep lung microbial dynamics and host-microbe interactions.
Lower respiratory tract harbour characteristic microbial communities. We explored the deep lung microbiota dynamics of the transplanted lung over time. Our study shows that a predominant "balanced" microbiota resembling that of a healthy lung is key for clinical stability and immune homeostasis.
After the Paper
What happened after your paper was published - and what impact did it have on your career?
Starting a new face: from biochemistry to the biology of biofilms
After working with bacterial biofilms as model to understand the evolution of enzymes in complex environments, it was hard to go back to domesticated bacteria. In my new lab we will continue to bridge between biofilms' biology and evolutionary biochemistry.
Coronaviruses: past, present and future
Share your research, thoughts and experience on the coronavirus family.
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From the editors
News, policy and social updates from the editors of Nature Microbiology and microbiology editors of other Nature titles
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Probiotics, microbiota and human health: Sifting hope from hype
A report on the 10th India Probiotic Symposium: Cutting-edge science and applications: Intestinal microbiota and probiotics. February 29 – March 1, 2020, New Delhi, India.
