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An early selection for a life-long health

In general, the enteric microbiota composition is relatively stable due to the ongoing competition of bacterial members for space and nutrients. Newly arriving bacteria hardly find an empty niche and sufficient nutrients to thrive and colonize. Shortly after birth, however, this situation is markedly different. The neonate is born sterile and newly incoming bacteria can easily find a place and nutrients to stay and colonize the neonate's intestinal mucosa. Notably, it is generally thought that this process is mainly driven by exposure to bacteria derived e.g. from the mother of the environment. But is that really true? If only the environment determines the microbiota composition couldn't that go terribly wrong? Shouldn't we expect that host factors influence the emerging microbiota ensuring a beneficial bacterial composition?
Go to the profile of Mathias Hornef
Aug 08, 2018

Centenary of 1918 influenza pandemic

A hundred years ago, a pandemic of influenza virus stunned the world, killing millions and frightening many more. We remain vulnerable to such outbreaks, but lessons learned from the past, a century of research and international cooperation could (and should) help prepare us for future pandemics

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