Written by Cui-Jing Zhang and Meng Li

Cancer patients respond differently to therapies. Our latest research has found that the success of the classical treatment methods depends on the composition of the microbiome in the gut, in particular several key specific bacteria.

To our knowledge, this is the most comprehensive prospective study investigating the longitudinal impact of acute HIV-1 infection in an HIV-1 hyperendemic area such as the Manhiça district in Mozambique. This unique study confirms and extends previous findings in non-human primate models and provides critical insights into the impact of infections in the gut microbiome as well as into the pathogenesis of HIV-1 infection.