Optimizing Lab Engines

Quantification of strain-specific differences in seven widely used strains of E. coli (BL21, C, Crooks, DH5a, K-12 MG1655, K-12 W3110, and W) using genomics, phenomics, transcriptomics, and genome-scale modeling.

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Dec 05, 2016
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In the Paper a group studied various strains of E. coli using genomics, phenomics, transcriptomics, and genome-scale modeling.The highlight of this study is they checked the performance of E. coli strains under different conditions (Transcriptomic data GSE78756) which enhances understanding of optimization as well selection of strain suitable for use either for basic biology or for industrial use. The transcription factors, codon usage and global regulators rpoS also plays vital role in gene expression. Finally paper introduces a new star method format brought by Cell press.

Paper Link : http://www.sciencedirect.com/science/article/pii/S2405471216302903

Go to the profile of Gaurav Gunjal

Gaurav Gunjal

Project Assistant, Indian Institute of Science, Bangalore, India

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