Most of us are familiar with the term “Inflammatory Bowel Disease (IBD)”. However, you likely have not heard about “Inflammatory Phyllosphere Disease (IPD)”. This is because I have just made it up to draw your attention, and to describe a form of dysbiosis in plants that we have just reported.
Cancer patients respond differently to therapies. Our latest research has found that the success of the classical treatment methods depends on the composition of the microbiome in the gut, in particular several key specific bacteria.
Many disease-causing bacteria secrete pore-forming toxins that target the plasma membrane of host cells. We uncovered a counter defence response by the host involving the release of extracellular vesicles, defensosomes, downstream of innate immune activation of autophagy proteins.
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