Behind the paper

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An early selection for a life-long health

In general, the enteric microbiota composition is relatively stable due to the ongoing competition of bacterial members for space and nutrients. Newly arriving bacteria hardly find an empty niche and sufficient nutrients to thrive and colonize. Shortly after birth, however, this situation is markedly different. The neonate is born sterile and newly incoming bacteria can easily find a place and nutrients to stay and colonize the neonate's intestinal mucosa. Notably, it is generally thought that this process is mainly driven by exposure to bacteria derived e.g. from the mother of the environment. But is that really true? If only the environment determines the microbiota composition couldn't that go terribly wrong? Shouldn't we expect that host factors influence the emerging microbiota ensuring a beneficial bacterial composition?
Go to the profile of Mathias Hornef
Aug 08, 2018
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Nature Reviews Disease Primers on Influenza. Not just another review on influenza, but a CEIRS review.

When Nature Reviews Disease Primers asked me to assemble a group of experts to write an article summarizing influenza disease, I immediately thought of bringing together scientific members from the Centers of Excellence in Influenza Research and Surveillance (CEIRS) to talk about the different aspects of the virus biology and pathogenesis, the disease, the existing countermeasures, and the possible future solutions to eliminate the burden that influenza virus imposes in human and animal health.
Go to the profile of Adolfo García-Sastre
Jul 08, 2018