Resistance by the world’s most deadly infectious disease
HIV appears to be developing resistance to drug treatments
Zika is not the only virus hitting the headlines this week: it seems some HIV strains are becoming resistant to the Tenofovir drug, reported in The Lancet Infectious Diseases journal this week. With a rather hefty list of authors, this paper investigated tenofovir resistance in 1926 patients from 36 countries,, finding a remarkable discrepancy between resistance rates, ranging from 20% in Europe to >50% in sub-Saharan Africa, attributed, at least in part, to the frequency of viral load monitoring. BBC report here.
Anti-microbial resistance is an ever-increasing issue worldwide, and is further discussed in this month’s issue of Nature Microbiology: in the Editorial, and a Comment by Roberto Kolter and Gilles van Wezel.