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Do microbes cause Alzheimer's?

A new study presents experimental evidence that the Alzheimer's may be caused by invading microbes.

Go to the profile of Ben Libberton
May 27, 2016
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New research presented in S@#?%&* Translational Medicine suggests that Alzheimer's Disease can develop in response to a microbial infection. Scientists at Harvard Medical School showed that the amyloid plaques associated with Alzheimer's were able to protect against meningitis in mice.

Aβ amyloid fibrils were produced in the brain and bound to invading pathogens, eventually encapsulating them in a "prison".

This has never been show in humans and whether or not infection could really be a clinical cause of Alzheimer's Disease remains to be seen. At the very least though, inflammation pathways could now be investigated as new targets for the treatment/prevention of Alzheimer's.

http://stm.sciencemag.org/content/8/340/340ra72


Image attribution - Neil Conway used from Flickr under Creative Commons.

https://www.flickr.com/photos/neilconway/379290641...

Go to the profile of Ben Libberton

Ben Libberton

Communications Officer, MAX IV Laboratory

I'm a Communications Officer at MAX IV Laboratory in Lund, Sweden, formally a Postdoc in the biofilm field. I'm interested in how bacteria cause disease and look to technology to produce novel tools to study and ultimately prevent infection. Part of my current role is to find ways to use synchrotron radiation to study microorganisms.

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